Complex migraines are getting worse. Why?

Triggers. Triggers may be responsible such as lack of sleep, stress, food, alcohol, menses, etc. Medication rebound can also be a factor with use of over the counter drugs, opioids, or triptans more than twice a week or butalbital combinations more than 5 days per month. Occasionally, birth control pills with estrogen can make migraines worse and may be contra-indicated in this type of migraine.