Cancers cause. Trouble by leasving their home base, entering the blood stream, exiting it, *building a new blood supply* and growing. They also have to evade the surveillance immune system. Eash step comlex molecular path. The most famous anti-angiogenesis drug is bevasuzumab, but many small molecules do similar work. Cut off the blood supply; kill th tumor. The develoment of the heart depends on these paths.