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Do hallucinogenic mushrooms alter serotonin levels?
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Dr. Pamela Pappas
Psychiatry
In brief: Magic mushrooms
Hallucinogenic mushrooms in the psilocybe genus do impact the serotonin system. They contain psilocybin and a related metabolite, which are structurally related to serotonin and are about 100 times less potent than lsd.
Partial agonist activity at 5-ht2a receptors mediates the psychedelic effect of hallucinogens like psilocybin, lsd, and mescaline (found in peyote).

In brief: Magic mushrooms
Hallucinogenic mushrooms in the psilocybe genus do impact the serotonin system. They contain psilocybin and a related metabolite, which are structurally related to serotonin and are about 100 times less potent than lsd.
Partial agonist activity at 5-ht2a receptors mediates the psychedelic effect of hallucinogens like psilocybin, lsd, and mescaline (found in peyote).
Dr. Pamela Pappas
Dr. Pamela Pappas
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