Can thyroid nodules grow again after rai?

Variables. Radioactive Iodine treatment for hyperthyroidism tends to have a much higher success rate than medications. Depending on the dose of radioactive iodine chosen, and the disease under treatment (Grave's vs toxic goitre, vs hot nodule etc), success rate in achieving definitive resolution of the hyperthyroidism may vary from 75-100%. A major expected side effect of radioactive iodine in hypothyroidism.