2 doctors weighed in:
If a drug has reached steady state, and then its dose increased, will the drug have a new steady state?
2 doctors weighed in

Dr. Richard Bensinger
Ophthalmology
1 doctor agrees
In brief: Yes
Drug concentration depends upon exposure (ingestion, injection, infusion) and the bodies means for disposal (metabolism, excretion by urine or liver, spontaneous breakdown).
Generally the more administered, the higher the concentration in the body and so a new higher steady state is reached with increased intake by whatever route.

In brief: Yes
Drug concentration depends upon exposure (ingestion, injection, infusion) and the bodies means for disposal (metabolism, excretion by urine or liver, spontaneous breakdown).
Generally the more administered, the higher the concentration in the body and so a new higher steady state is reached with increased intake by whatever route.
Dr. Richard Bensinger
Dr. Richard Bensinger
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