2 doctors weighed in:

Is it safer to take Benadryl (diphenhydramine) or hydroxyzine while taking tramadol 75-100mg?

2 doctors weighed in
Dr. John Chiu
Internal Medicine - Allergy & Immunology
1 doctor agrees

In brief: Neither is better

Since both of the drugs have sedating effects, the choice would depend on which sedates you less or more (depending on your goal).
Neither interacts with tramadol otherwise.

In brief: Neither is better

Since both of the drugs have sedating effects, the choice would depend on which sedates you less or more (depending on your goal).
Neither interacts with tramadol otherwise.
Dr. John Chiu
Dr. John Chiu
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