2 doctors weighed in:

Why sickle cell anemeia / multiple myeloma cause diabetes insipidus ? Is it because it may obstruct the blood flow to the kidneys and damage them?

2 doctors weighed in
Dr. Ed Friedlander
Pathology
1 doctor agrees

In brief: Basically right

Even sickle cell trait ruins much of the concentrating ability of the kidneys by adulthood.
Myeloma is more likely to damage and obstruct the tubules themselves. Both produce a kidney lesion that prevents the urine from becoming concentrated, rather than a pituitary diabetes insipidus.

In brief: Basically right

Even sickle cell trait ruins much of the concentrating ability of the kidneys by adulthood.
Myeloma is more likely to damage and obstruct the tubules themselves. Both produce a kidney lesion that prevents the urine from becoming concentrated, rather than a pituitary diabetes insipidus.
Dr. Ed Friedlander
Dr. Ed Friedlander
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