13 doctors weighed in:
Whats cause and effect of brca1 gene on breast cancer?
13 doctors weighed in

10 doctors agree
In brief: Genetic mutation
Genetic mutation in long arm of chromosome 17 in brca 1 , in 13 brca 2, instead of normal protective proteins which control abnormal growth of cell , repair broken down dna, maintain genetic stability, the abnormal proteins fail to protect, and responsible for 40% inherited breast cancers, 80% of breast & ovarian cancers.

In brief: Genetic mutation
Genetic mutation in long arm of chromosome 17 in brca 1 , in 13 brca 2, instead of normal protective proteins which control abnormal growth of cell , repair broken down dna, maintain genetic stability, the abnormal proteins fail to protect, and responsible for 40% inherited breast cancers, 80% of breast & ovarian cancers.
Dr. Addagada Rao
Dr. Addagada Rao
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Dr. Amr Azim
Fertility Medicine
2 doctors agree
In brief: Defect in DNA repair
Brca1 is a large protein involved in repairing dna damage.
Deficiency in this protein due to mutation of brca1 gene leads to defective repair of damage to dna that leads to uncontrolled proliferation of cells and cancer.

In brief: Defect in DNA repair
Brca1 is a large protein involved in repairing dna damage.
Deficiency in this protein due to mutation of brca1 gene leads to defective repair of damage to dna that leads to uncontrolled proliferation of cells and cancer.
Dr. Amr Azim
Dr. Amr Azim
Thank
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