Is esophageal perforation due to bisphosphonates?

Can be. Bisphosphonates are one of the medicines that can erode the esophageal lining if in contact for a while. That is why the directions say to take it with food or water and stay upright (sitting up or standing) for at least 30 minutes after. Two other common medications that can do this too are calcium tablets and doxycycline.

Related Questions

How long after an EGD can you develop an esophageal perforation? I had an EGD 10 days ago & still have a really sore throat.

Egd. Esophageal perforation after EGD is very rare and occurs acutely within days after the procedure. Clinical risk factors include difficult procedure, male sex, and patients over the age of 60 based on limited clinical evidence. If you have acute chest pain with radiation to the back or shoulder or acute vomiting, you should go to the ER right away. Read more...