2 doctors weighed in:

Accutane vs bactrim (sulfamethoxazole and trimethoprim) acne help!, what to do?

2 doctors weighed in
Dr. Ed Friedlander
Pathology
1 doctor agrees

In brief: First try

"bactrim" isn't as good as some of the other antibiotics, especially the tetracyclines.
Don't ever use an antibiotic as sole treatment for acne. Isotretinoin / Accutane is your last resort unless you have cystic acne, for which nothing else will probably work. It's not for the faint-hearted but is a remarkably effective medication.

In brief: First try

"bactrim" isn't as good as some of the other antibiotics, especially the tetracyclines.
Don't ever use an antibiotic as sole treatment for acne. Isotretinoin / Accutane is your last resort unless you have cystic acne, for which nothing else will probably work. It's not for the faint-hearted but is a remarkably effective medication.
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