18 doctors weighed in:
How do cleft lip and palate develop?
18 doctors weighed in

Dr. Otto Placik
Surgery - Plastics
8 doctors agree
In brief: Failure of fusion
There are essentially three layers in the developing embryo and it is felt that failure of the middle layer to advance and fuse in the face (from the frontonasal process of the bronchial arches) maybe responsible.
While socioeconomic factors and nutrition play a role, genetic factors are also contributory.

In brief: Failure of fusion
There are essentially three layers in the developing embryo and it is felt that failure of the middle layer to advance and fuse in the face (from the frontonasal process of the bronchial arches) maybe responsible.
While socioeconomic factors and nutrition play a role, genetic factors are also contributory.
Dr. Otto Placik
Dr. Otto Placik
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Dr. Roxanne Sylora
Surgery - Plastics
7 doctors agree
In brief: Birth defect
The formation of a face is a complicated process involving fusion of different tissues and cell types.
Cleft lip and/or palate are caused by failure of those processes to proceed as they normally do. There is a spectrum of abnormailities that fall into this category.

In brief: Birth defect
The formation of a face is a complicated process involving fusion of different tissues and cell types.
Cleft lip and/or palate are caused by failure of those processes to proceed as they normally do. There is a spectrum of abnormailities that fall into this category.
Dr. Roxanne Sylora
Dr. Roxanne Sylora
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Dr. Marguerite Barnett
Surgery - Plastics
6 doctors agree
In brief: Failure to develop
Cleft lip and palate develop or rather, fail to develop in utero.
When the fetus is just around two months old, protuberances start in the head area and coalesce to form the face. If these protuberances fail to fuse, a cleft develops. A cleft can develop in many different sites but the most common are in the upper lip and upper palate. 1 in 700 babies will have a cleft.

In brief: Failure to develop
Cleft lip and palate develop or rather, fail to develop in utero.
When the fetus is just around two months old, protuberances start in the head area and coalesce to form the face. If these protuberances fail to fuse, a cleft develops. A cleft can develop in many different sites but the most common are in the upper lip and upper palate. 1 in 700 babies will have a cleft.
Dr. Marguerite Barnett
Dr. Marguerite Barnett
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Dr. Clark Schierle
Surgery - Plastics
1 doctor agrees
In brief: Cleft Lip / Palate
The facial features that form the lip and palate fuse in weeks six through eight of gestation.
When this process fails due to genetic or environmental factors, a cleft lip or palate result.

In brief: Cleft Lip / Palate
The facial features that form the lip and palate fuse in weeks six through eight of gestation.
When this process fails due to genetic or environmental factors, a cleft lip or palate result.
Dr. Clark Schierle
Dr. Clark Schierle
Thank
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