1 doctor weighed in:

Can prolactinomas build tolerance to medication?

1 doctor weighed in
Dr. Philip Kern
Internal Medicine - Endocrinology

In brief: Tolerance

Yes, sometimes higher doses of Cabergoline or bromocriptine are needed.
It could be drug tolerance, or it could be another medication or condition that is increasing prolactin. Usually the prolactinoma will shrink with treatment. Sometimes, relatively high doses of Cabergoline are needed. Talk to your endocrinologist.

In brief: Tolerance

Yes, sometimes higher doses of Cabergoline or bromocriptine are needed.
It could be drug tolerance, or it could be another medication or condition that is increasing prolactin. Usually the prolactinoma will shrink with treatment. Sometimes, relatively high doses of Cabergoline are needed. Talk to your endocrinologist.
Thank