Are all my symptoms related-abnormal upep, heel pain, fatigue, joint, pain, stable bone lesion on tibia also sensory neuropathy?

Unlikely. It is unlikely that they are all related. Have it evaluated and get the appropriate treatment.
Probably not. Neuropathy and bone lesion are not usually related. However neuropathy and inflammatory arthrities are. Not sure what upep is but GI issues and arthrities can be related via seronegative arthropathies.

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