Variable. A mass or lump. Difficulty swallowing. Change in bowel or bladder habits. Bloody stool or urine. Abnormal bleeding in a woman. Unexplained weight loss. Chest infection. Unexplained cough. Unexplained anemia. New onset of seizures. Personality change. New inversion of a nipple. Sudden accumulation of fluid in a body cavity. Change in a wart / mole. Sense of fullness in the abdomen.
Multiple. From skin to lung, to, GI tract. But weakness, pallor, weight loss, some with fever, and then local symptoms from the organ involved. Lung-cough blood rectum: bleeding.