Is dopaminergic pathway involved in drug addiction?

Yes. All drugs of abuse activate the Dopamine system in the reward pathway.
Addiction dopamine. Dopamine has been the traditional model in addiction. However studies, autopsies and empirical treatment outcome show that gaba pathways may be even more important in addiction. Enoch et al 2012 onfirmed the involvement of the gabaergic system in alcoholism but also reveals a hippocampal gaba input in Cocaine addiction. This findings concurs with high success rates using gabapenting with addicts.