How can you tell the difference between sciatica and a blood clot? If there is no back or hip pain, just leg pain above the knee. Ty

Generally you can't. Unless you have a fever or swollen limb which may suggest a clot more than sciatica otherwise not very specific. I would suggest ruling out the clot first and then workup the sciatica issue afterwards.
Yes. A good clinician can usually make that differentiation rather easily. A simple ultrasound will rule out a blood clot.

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