8 doctors weighed in:

How likely is it that I have colorectal cancer if my dad had it?

8 doctors weighed in
Dr. Joseph Woods
Pathology
3 doctors agree

In brief: More likely.

Most colon cancer is from adenomatous polyps.
Hereditary nonpolyposis colon cancer comes from hmsh2 and hmlh1 genes on chromosomes 2 and 3 respectively which repair dna. These have mutations that can lead to colon and other cancers. Diagnosis needs three or more relatives with colon cancer, with one being a first degree relative, >1 case before 50, and >=2 generations.

In brief: More likely.

Most colon cancer is from adenomatous polyps.
Hereditary nonpolyposis colon cancer comes from hmsh2 and hmlh1 genes on chromosomes 2 and 3 respectively which repair dna. These have mutations that can lead to colon and other cancers. Diagnosis needs three or more relatives with colon cancer, with one being a first degree relative, >1 case before 50, and >=2 generations.
Dr. Joseph Woods
Dr. Joseph Woods
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1 comment
Dr. Ed Friedlander
You'd do well to actually go through with the recommendation for occasional colonoscopy. This will massively reduce your risk of actually dying of the disease. Good luck. There are other family syndromes that aren't known, as Dr. Wood suggested.
Dr. Carlo Contreras
Surgery - Oncology
1 doctor agrees

In brief: Need more info

The number varies quite a bit depending on if you and your father share genes that correspond to a syndrome, or if your father has a sporadic case of colorectal cancer.
Generally, if your father was diagnosed before the age of 50, then your risk is considerably higher than the general population.

In brief: Need more info

The number varies quite a bit depending on if you and your father share genes that correspond to a syndrome, or if your father has a sporadic case of colorectal cancer.
Generally, if your father was diagnosed before the age of 50, then your risk is considerably higher than the general population.
Dr. Carlo Contreras
Dr. Carlo Contreras
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Dr. Robert Cloud
Surgery - Colorectal

In brief: Family history colon

3 times the risk over someone who has no family history.
You should start colonoscopies screening at age 40 or 10 years before the age your father was when he was diagnosed, whichever is earlier,

In brief: Family history colon

3 times the risk over someone who has no family history.
You should start colonoscopies screening at age 40 or 10 years before the age your father was when he was diagnosed, whichever is earlier,
Dr. Robert Cloud
Dr. Robert Cloud
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Dr. Helmy Guirgis
Internal Medicine - Hematology & Oncology

In brief: How old?

Sporadic colo-rectal cancers usually occur in older patients say over 50.
The hereditary cancer usually occurs in younger patients. There are tests to diagnose this hereditary type with 90% sensitivity and specificity approximately. The familial type is the one we suspect that a family has it but has not yet tested. How old are you and dad, other relatives?

In brief: How old?

Sporadic colo-rectal cancers usually occur in older patients say over 50.
The hereditary cancer usually occurs in younger patients. There are tests to diagnose this hereditary type with 90% sensitivity and specificity approximately. The familial type is the one we suspect that a family has it but has not yet tested. How old are you and dad, other relatives?
Dr. Helmy Guirgis
Dr. Helmy Guirgis
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