Why only sometimes I notice the veins of the back of my hands are more visible and enlarged looking? I'm only in my 20's.

Swollen hand veins. Hand veins can swell for many reasons but the most common is certainly hereditary . Other factors would be level of hydration, aging, sun exposure and loss of elasticity and volume. Actually, I am amazed at the amount of women that i see with bulging hand veins. They can be easily treated with laser or sclerotherapy and usually a combination of both.