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What percent of women inherit a brca1 or brca2 gene?

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Dr. Romeo Mandanas
Internal Medicine - Hematology & Oncology

In brief: Clarifying Q & A

In the general population, the incidence of a brca1 mutation is between 1:500 to 1:800.
It is much lower for brca2. For a woman or offspring to inherit the gene from a parent who has one copy of the mutated gene, there is a 50% chance of acquiring the gene in question. It is autosomal dominant and therefore can manifest its deleterious consequences by itself without need of a second copy.

In brief: Clarifying Q & A

In the general population, the incidence of a brca1 mutation is between 1:500 to 1:800.
It is much lower for brca2. For a woman or offspring to inherit the gene from a parent who has one copy of the mutated gene, there is a 50% chance of acquiring the gene in question. It is autosomal dominant and therefore can manifest its deleterious consequences by itself without need of a second copy.
Dr. Romeo Mandanas
Dr. Romeo Mandanas
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