I have always had really clear skin, but for the last few weeks my face has broken out! But the pimples/bumps are large and painful with no whitehead?

Get seen now. This may not even be real acne, but some other sort of papular eruption. A dermatology appointment is in order. If you are taking any new medication, stop now.
Just from the small. Amt. You have already shared - would encourage you to work with a dermatologist. In meantime: wash face w gentle cleanser 2x/day ; use oil free products. No oily hair or heavy foundations. Exfoliate occasionally. Try not to pop pimples. Avoid touching face (cradling chin in hands). Remove makeup before bed. Shower after strenuous exercise. Consider otc products (salicylic acid or benzoyl peroxide).

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Seldom have pimple/cystic acne. ONE cystic appeared 1mnth ago, no longer red but big bump remain & it won't come to a head. How do I treat it?

Let it be. Leaving it alone is the best option. You may try warm fomentation. Do not try to pop it as that will only lead to a scar. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco or alcohol in any form. Practice safe sex. Get HPV vaccine. Read more...

3 weeks ago I broke out on my face with red, dry patches of skin. Mainly under nose and around my mouth. What is it? 49 female. Hardly ever had acne and no history of skin disorders. It started out like a rash with pimples. The bumps are gone but the

It . It sounds like you have something called perioral dermatitis. This can be a common rash in women, especially this time of year. It tends to wax and wane but usually doesn't go away with out proper treatment. Treatment usually consists of a combination of a topical cream and an oral antibiotic. I recommend a trip to your dermatologist to confirm the diagnosis and to get the proper treatment to make you better. Good luck. Read more...
See your doctor. Contact dermatitis presents the way you described and can be a result of your skin being sensitized to a cream, soap, preservative, pillow fabric etc. There are other potential diagnoses which will require an exam by a dermatologist to rule out other inflammatory skin conditions which can be treated with the right medication. Read more...