I've noticed on my z pack it says no antiacids 2 hours before ok can I take my omperazole after I taken my z pack what's the deal here?

Azithromycin. Azithromycin taken at the same time as aluminum- or magnesium- based antacids, such as mylanta or maalox may result in binding of the Azithromycin and prevent it from being absorbed from the intestine. Taken on an empty stomach this may lead to gastric upset, and food will delay absorption. You can take Omeprazole after you have taken the azithro.