I saw this guy with huge eyes like an owl. It was really strange. What kind of deformity would cause this?

When a persons eyes. are prominent and seem to protrude out of the socket (bony orbit), it is usually a sign of hypertrophic (overgrowth) retro-orbital fat or even extra-ocular muscle inflammation. There are a few conditions associated with this but the most common is hyper-thyroidism. .