Is erythroblastosis fetalis is an example of autoimmunity or isoimmunity?

Alloimmunity. Autoimmunity is an immune response to one's own proteins while the example of Erythroblastosis fetalis is an immune response of mom's antibodies to a foreign antigen, this case from the fetus.

Related Questions

Can you please define erythroblastosis fetalis?

Hemolytic disease. Erythroblastosis fetalis is also called hemolytic disease. Babies develop this condition before they are born. Erythroblastosis fetalis occurs when you and your baby have different blood types. When your baby's blood mixes with your blood during pregnancy, your immune system reacts by making antibodies against it. Read more...

Why does erythroblastosis fetalis only occur due to Rh factors?

Misconception. It is a misconception that erythroblastosis fetalis can only occur in rh negative moms who carry a Rh pos baby. Mom can develop antibodies against a variety of other components of the human blood system that can cause erythroblastosis in the baby - fortunately these conditions are rare. Read more...

My baby died due to erythroblastosis fetalis is there still a chance for me to have another pregnacy and have a normal baby?

Erythroblastosis Fet. Yes you, however, you will need very close follow up and should be seeing someone specialized in the care and treatment of this condition. A pre-conceptual consult with a Maternal-Fetal Medicine specialist can get into the details of the special monitoring you will need. Read more...
Several chances. The father may have only a 50/50 chance of transmitting the gene of the protein that your blood reacts to and attacks causing anemia. Then, if it is present and the baby has blood that your blood reacts to, transfusion can be done in utero (it is risky) http://www.merckmanuals.com/professional/gynecology_and_obstetrics/abnormalities_of_pregnancy/erythroblastosis_fetalis.html. Read more...

If an rh-positive baby is suffering from erythroblastosis fetalis. An exchange transfusion is performed, why?

Increase RBC mass. Most likely the mother is Rh neg. and has made anti-Rh antibodies destroying baby's Rh pos. red cells. Exchange transfusion to the baby with Rh neg. blood will prevent hemolysis or transfused blood and increase oxygen capacity for the newborn. This process will also decrease the amount of bilirubin in baby's plasma and prevent kernicterus (yellow staining seen in parts of the brain) Read more...

An rh-positive baby is suffering from erythroblastosis fetalis. Why would an exchange transfusion be performed?

Increase RBC mass. Most likely the mother is Rh neg. and has made anti-Rh antibodies destroying baby's Rh pos. red cells. Exchange transfusion to the baby with Rh neg. blood will prevent hemolysis or transfused blood and increase oxygen capacity for the newborn. This process will also decrease the amount of bilirubin in baby's plasma and prevent kernicterus (yellow staining seen in parts of the brain) Read more...
Complex but simple. The increase in the bilirubin (dangerous) reflects a destruction of the babies red cells by antibodies. If you REMOVE the babies cells that are fragile & breaking down & replace them with ones that don't, then the destruction slows/stops. The exchange blood lasts long enough for the babies body to catch up with any left over jaundice & get on with being a newborn. Read more...