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For how long does hydrocodone/acetaminophen last?

1 doctor weighed in
Dr. Alan Wartenberg
Addiction Medicine

In brief: Last??

For pain, the useful period is generally 3-4 hours.
If you mean how long does it stay in the body, it is rapidly metabolized and is only in the bloodstream in that form for a couple hours, is metabolized to Codeine and morphine, and those metabolites can last a day or two and be detected in urine, but they are not producing much activity, same with the tylenol (acetaminophen) in it.

In brief: Last??

For pain, the useful period is generally 3-4 hours.
If you mean how long does it stay in the body, it is rapidly metabolized and is only in the bloodstream in that form for a couple hours, is metabolized to Codeine and morphine, and those metabolites can last a day or two and be detected in urine, but they are not producing much activity, same with the tylenol (acetaminophen) in it.
Dr. Alan Wartenberg
Dr. Alan Wartenberg
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