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What does "mast cell degranulation" mean in an allergic reaction?

5 doctors weighed in
Dr. Michael Fisher
Dermatology
4 doctors agree

In brief: Mast cell

Definition protein involved in mast cell degranulation.
Mast cell is a large, ovoid cell of hematopoietic lineage, with a centrally located nucleus and numerous large, intensely basophilic granules. The binding of an antigen to its specific immunoglobulin-e antibody on the mast cell surface triggers the release of the mc granules. Mast cells are involved in hypersensitivity reactions.

In brief: Mast cell

Definition protein involved in mast cell degranulation.
Mast cell is a large, ovoid cell of hematopoietic lineage, with a centrally located nucleus and numerous large, intensely basophilic granules. The binding of an antigen to its specific immunoglobulin-e antibody on the mast cell surface triggers the release of the mc granules. Mast cells are involved in hypersensitivity reactions.
Dr. Michael Fisher
Dr. Michael Fisher
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