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Would a blood transfusion affect immunity?

1 doctor weighed in

In brief: Yes

Transfusion-associated immuno-modulation (TRIM) is independent of whether the blood is allogenic, autogenic, or leukodepleted.
This has been described since 1973, seen in the improved graft survival in kidney transplant in transfused patients. Some effects include down-regulation of the immune function by decreasing cytokine production, and an increase in T suppressor cell number and function.

In brief: Yes

Transfusion-associated immuno-modulation (TRIM) is independent of whether the blood is allogenic, autogenic, or leukodepleted.
This has been described since 1973, seen in the improved graft survival in kidney transplant in transfused patients. Some effects include down-regulation of the immune function by decreasing cytokine production, and an increase in T suppressor cell number and function.
Dr. Juan Merayo-Rodriguez
Dr. Juan Merayo-Rodriguez
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