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Can you explain neoadjuvant therapy in cancer treatment?

9 doctors weighed in
Dr. Della Howell
Pediatrics - Hematology & Oncology
7 doctors agree

In brief: Neoadjuvant therapy

Is typically used when a patient needs a tumor surgically removed but the doctors think it would be best to shrink the tumor some before the surgery actually happens.
Neoadjuvant therapy can be chemotherapy and/or radiation therapy. Typically, after a few weeks of this treatment, the surgeons remove the tumor, hopefully with greater success than they would have had before the additional therapy.

In brief: Neoadjuvant therapy

Is typically used when a patient needs a tumor surgically removed but the doctors think it would be best to shrink the tumor some before the surgery actually happens.
Neoadjuvant therapy can be chemotherapy and/or radiation therapy. Typically, after a few weeks of this treatment, the surgeons remove the tumor, hopefully with greater success than they would have had before the additional therapy.
Dr. Della Howell
Dr. Della Howell
Thank
Dr. Barry Rosen
Surgery
4 doctors agree

In brief: Preoperative ChemoRx

Traditionally, chemotherapy is given after surgery, based on the staging information obtained at the time of surgery.
However, some cancers are better-treated with chemorx (and/or radiationrx) before surgery. For example, larger breast tumors can be shrunk with chemorx, thus enabling rx by lumpectomy rather than mastectomy; some people w/rectal ca avoid permanent colostomy w/chemo+radrx pre-op.

In brief: Preoperative ChemoRx

Traditionally, chemotherapy is given after surgery, based on the staging information obtained at the time of surgery.
However, some cancers are better-treated with chemorx (and/or radiationrx) before surgery. For example, larger breast tumors can be shrunk with chemorx, thus enabling rx by lumpectomy rather than mastectomy; some people w/rectal ca avoid permanent colostomy w/chemo+radrx pre-op.
Dr. Barry Rosen
Dr. Barry Rosen
Thank
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