I use computer a lot at work, do you have any recommendations for a wrist splint/guard/support or any other methods to protect my wrist?
Ergonomics. A splint will not help as much as an ergonomic desk. You want your feet on the ground and your back straight in a good a Support chair. Your wrists need to be straight with your elbows bent at 90 deg. So you might need a pullout drawer. The splint will only help teach you the position.