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Do neurotransmitter levels return to normal after getting over depression?

7 doctors weighed in
Dr. Steven Reidbord
Psychiatry
6 doctors agree

In brief: Levels not abnormal

Many people don't realize there is no documented "chemical imbalance" in depression — no measurable differences in neurotransmitter levels in depressed vs nondepressed subjects.
That's why there's no blood test for depression. What we do know is that antidepressants change the levels of neurotransmitters, and this is associated with beneficial effects. The effect ends when the meds are stopped.

In brief: Levels not abnormal

Many people don't realize there is no documented "chemical imbalance" in depression — no measurable differences in neurotransmitter levels in depressed vs nondepressed subjects.
That's why there's no blood test for depression. What we do know is that antidepressants change the levels of neurotransmitters, and this is associated with beneficial effects. The effect ends when the meds are stopped.
Dr. Steven Reidbord
Dr. Steven Reidbord
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