High-grade glioma brain tumor, what to do?

Get best care. The optimal care for a high grade glioma will often be found at a major academic medical center. Treatment is first surgery, to remove the maximum amount of tumor possible, followed by radiation and chemotherapy, often together. All of this also requires good neuroradiology, good neuropathology, good nursing care and supportive care of all types. Don't be shy about asking for second opinions.