Gettin under ur skin. Impetigo can occur when a germ, usually a strep or staph species, gets into the skin--often through a small scratch or wound. The germ can be in nasal passages or on your skin, esp hands and fingers. There are antibiotic ointments that can help it clear; sometimes oral antibiotics are necessary if it is widespread. Washing hands and using hand gels can keep it away! may need to see your dr for rx.