3 doctors weighed in:

Can polymyxins work to treat pseudomonas aeruginosa?

3 doctors weighed in
Dr. Michael DePietro
Internal Medicine - Pulmonary Critical Care
1 doctor agrees

In brief: Yes

Polymyxins are a very old class of antibiotics.
They tend to have kidney and nervous system toxicity, and because they are very old the exact effective doses of these drugsis not well known. Still given problems with bacterial antibiotic resistance, sometimes these agents are used when a highly resistant bacteria is encountered. Colistin the one most often used can be given via inhalation or iv.

In brief: Yes

Polymyxins are a very old class of antibiotics.
They tend to have kidney and nervous system toxicity, and because they are very old the exact effective doses of these drugsis not well known. Still given problems with bacterial antibiotic resistance, sometimes these agents are used when a highly resistant bacteria is encountered. Colistin the one most often used can be given via inhalation or iv.
Dr. Michael DePietro
Dr. Michael DePietro
Thank
Dr. Michael Ein
Internal Medicine - Infectious Disease

In brief: Yes

Polymyxin b or colistin are used for pseudomonas and acinetobacter infections that are resistant to all other antibiotics.
As these drugs have significant renal toxicity they are reserved for infections resistant to less toxic antibiotics.

In brief: Yes

Polymyxin b or colistin are used for pseudomonas and acinetobacter infections that are resistant to all other antibiotics.
As these drugs have significant renal toxicity they are reserved for infections resistant to less toxic antibiotics.
Dr. Michael Ein
Dr. Michael Ein
Thank
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