2 doctors weighed in:

How does phosphate trigger pseudomonas aeruginosa infections?

2 doctors weighed in
Dr. Tony Ho
Internal Medicine - Infectious Disease

In brief: Inducible virulence

Pseudomonas demonstrates increased virulence when it is grown in an environment that starves it of phosphate; it affects expression of virulence genes when the organism detects low levels of phosphate.

In brief: Inducible virulence

Pseudomonas demonstrates increased virulence when it is grown in an environment that starves it of phosphate; it affects expression of virulence genes when the organism detects low levels of phosphate.
Dr. Tony Ho
Dr. Tony Ho
Thank
Dr. Michael DePietro
Internal Medicine - Pulmonary Critical Care

In brief: By changing genes

This is not completely understood, but there is experimental evidence from animal experiments and such, that the pseudomonas grown in a low phosphate environment will respond on changes in what genes the germ activates.
These changes lead the bacteria to make chemicals that increase its ability to grow and cause damage. In patients with low phosphate levels this may mean > risk of infection.

In brief: By changing genes

This is not completely understood, but there is experimental evidence from animal experiments and such, that the pseudomonas grown in a low phosphate environment will respond on changes in what genes the germ activates.
These changes lead the bacteria to make chemicals that increase its ability to grow and cause damage. In patients with low phosphate levels this may mean > risk of infection.
Dr. Michael DePietro
Dr. Michael DePietro
Thank
Read more answers from doctors