Later in life. Patients with cystic fibrosis often get these bacteria in their airways by adulthood. The vast majority of adult CF patients have airways colonized with pseudomonas aeruginosa (pa). Younger patients (kids) tend not to have pa in their airways, but that can vary.
Unlikely as a child. Pseudomonas aeruginosa is a bacterium that typically infects patients with CF in the second or third decade in life - the longer someone with CF lives the higher the odds of getting pseudomonas are. Additionally, the worse the patient's lung function is the higher the odds of getting p. Aeruginosa are. Not everyone with CF will get it during their lifetime - but most do (at this time).
CF registry. The CF registry has specific data to answer this question. The overall percentage of patients with p. Aeruginosa in 2006 was 55%, and by the age of 11 years, about 60% of patients will be colonized. I hope this helps.
Yes and No. Cystic fibrosis is not contagious but pseudomonas infections are.
My 2 year old son had a throat culture that came back with a high reading of pseudomonas, is this a sign of cystic fibrosis?
Need to rule CF out. I would have the culture repeated. Unfortunately, studies have shown 49% of 2 year olds had positive throat cultures for pseudomonas aeruginosa. Sweat testing and genetic testing should be performed. Check to see if newborn blood screen tested for cystic fibrosis (cf).
CF screening. Pseudomonas aeruginosa is one of the common bacteria involved in CF sinus and lung disease. It is found in some patients who have mechanical ventilation or in cases of exposure to contaminated water as well. You should inquire about a CF sweat test at your doctor's office to screen him for cf. Prmg respiratory pediatrics can review his records including growth chart (fax 858 259 9689).
Possible but small % Many people with cystic fibrosis have aspergillus (a fungus) in their airway, but in the vast majority of cases it does not cause disease. In a small percent of patients it may cause allergic bronchopulmonary aspergillosis (abpa), and that can lead to lung damage. Abpa can usually be treated.
Rare. Asperigillus is a rare complication of CF in the airway; it is more commonly seen after lung transplantation in the face of immune suppression drugs. Less than 1 in 1000 non transplanted patients with CF grow aspergillus out of a sputum culture.
Somewhat. The main risk for candida in patients with cystic fibrosis are for those patients who take inhaled drugs (such as combined therapies - advair, symbicort (budesonide and formoterol) & Dulera or monotherapies such as asthmanex, qvar, flovent). The inhaled steroids decrease bacterial counts in the mouth and increase the risk of fungal/candidal overgrowth resulting in thrush.
Possible. Depending on your child's lung function and airway clearance compliance, the chances vary somewhat. Candidiasis is rare in pre-adult sputum culture data sent on the CF foundation, except in children with very poor lung function tests who have already had multiple other infections.
Sometimes/immunity. Candida can be associated with colonization of the airway and mouth in cf. The fungus may live in the airway without actually causing an infection. If there are inhaled drugs or medications which affect local defenses, then the candida may result in an infection. A reference for your interest is: http://www. Ncbi. Nlm. Nih. Gov/pubmed/21067323. With a lung transplantation, patients are more prone.
No. Individuals with asthma are not at any higher risk to develop pseudomonas infection than general population. Exception would be when they develop a respiratory failure requiring ventilator support and ICU stay.
No. There is no known association between asthma and pseudomonas aeruginosa infections per se. Patients on high dose steroids who are hospitalized may be less able to fight off the infection - but there are no reported associations even in this extreme case.
No. Asthma does not predispose a person to a bateria such as pseudomonas. Very unlikely.