What is a good over-the-counter medication to take for an itchy throat? I have a minor cough, particularly when I am in bed. I drink lots of fluids.

Try antihistamine. Try otc antihistamine. More importantly, find out what may be triggering the itching and the cough. If the cough has been present for weeks or months, you may even have asthma.
Lots of Choices. There are lots of choices from lozenges to sprays. We do not provide any product endorsement here on health tap, but you have plenty of options at the grocery or drug store near you.