I have an ear infection and have been taking antibiotics for it! Can it affect my Depo-Provera provera (medroxyprogesterone) I'm on?

NOT REALLY.. Usual antibiotics used for ear infection shouldn't interfere with your Depo-Provera provera (medroxyprogesterone). Relax....!
No. I don't think antibiotics interfere with hormone metabolism.A major exception is Rifampin which is for TB among other things. It is best to check with the doctor who put you on DepoProvera .Hope your ear infection gets better soon.