11 doctors weighed in:

Are there any antibiotics that can be used to treat clostridium difficile infection?

11 doctors weighed in
Jin Packard
Emergency Medicine
7 doctors agree

In brief: Flagyl or Vancomycin

C. Difficile colitis almost always occurs when another oral antibiotic, used to treat a different infection, wipes out normal gut bacteria.
Patients who develop c.Diff colitis should stop taking that initial oral antibiotic. Treatment is usually with Metronidazole (flagyl) or vancomycin (vancocin). For severe cases, doctors may prefer vanco. Newer drugs are available if this treatment fails.

In brief: Flagyl or Vancomycin

C. Difficile colitis almost always occurs when another oral antibiotic, used to treat a different infection, wipes out normal gut bacteria.
Patients who develop c.Diff colitis should stop taking that initial oral antibiotic. Treatment is usually with Metronidazole (flagyl) or vancomycin (vancocin). For severe cases, doctors may prefer vanco. Newer drugs are available if this treatment fails.
Jin Packard
Jin Packard
Answer assisted by Jin Packard, Medical Student
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Dr. Michael Ein
Internal Medicine - Infectious Disease
1 doctor agrees

In brief: Yes

Flagyl, vancomycin or fidaxomicin are the antibiotics usually used to kill c.
Difficile overgrowth in the colonic lumen.

In brief: Yes

Flagyl, vancomycin or fidaxomicin are the antibiotics usually used to kill c.
Difficile overgrowth in the colonic lumen.
Dr. Michael Ein
Dr. Michael Ein
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Dr. John Leander Po
Internal Medicine - Infectious Disease
1 doctor agrees

In brief: Yes&alternatively...

Metronidazole or vancomycin by mouth.
The newer drug (though very expensive) is fidaxomicin. However, in severe cases, the infected colon must be removed by surgery. Emerging as an alternative method to antibiotics is stool transplantation where stool from a close partner can be used to repopulate the normal flora of a c difficile infected patient (gough et al. Clin infect dis. 2011;53:994-1002).

In brief: Yes&alternatively...

Metronidazole or vancomycin by mouth.
The newer drug (though very expensive) is fidaxomicin. However, in severe cases, the infected colon must be removed by surgery. Emerging as an alternative method to antibiotics is stool transplantation where stool from a close partner can be used to repopulate the normal flora of a c difficile infected patient (gough et al. Clin infect dis. 2011;53:994-1002).
Dr. John Leander Po
Dr. John Leander Po
Thank
1 comment
Dr. John Leander Po
Inconsistent data except for a handful of probiotics. Saccharomyces boulardii is an example.
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