8 doctors weighed in:

How can taking antibiotics cause clostridium difficile infection?

8 doctors weighed in
Dr. Booth Wainscoat
Internal Medicine - Infectious Disease
5 doctors agree

In brief: Colon imbalance

Every person has an ideal balance of different helpful bacteria (flora) in their colon.
Disrupting that balance can lead to diarrhea, cramping & gas. Almost all antibiotics have the ability to disrupt the gut flora. Friendly bacteria are sacrificed during antibiotic use allowing unfriendly bacteria like clostridium difficile to grow. Some c. Difficile produce a toxin which can destroy the colon.

In brief: Colon imbalance

Every person has an ideal balance of different helpful bacteria (flora) in their colon.
Disrupting that balance can lead to diarrhea, cramping & gas. Almost all antibiotics have the ability to disrupt the gut flora. Friendly bacteria are sacrificed during antibiotic use allowing unfriendly bacteria like clostridium difficile to grow. Some c. Difficile produce a toxin which can destroy the colon.
Dr. Booth Wainscoat
Dr. Booth Wainscoat
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Dr. John Leander Po
Internal Medicine - Infectious Disease
1 doctor agrees

In brief: Alters gut flora

Every person's colon has a profile of normal microbes that overwhelms the ability of most "bad" bacteria (like c difficile) from growing and causing harm. However, when antibiotics are used for infections (levofloxacin or cephalexin), a great number of bacteria normally found in the colon are also killed, allowing for the overgrowth of c difficile (resistant to the initial antibiotic used).

In brief: Alters gut flora

Every person's colon has a profile of normal microbes that overwhelms the ability of most "bad" bacteria (like c difficile) from growing and causing harm. However, when antibiotics are used for infections (levofloxacin or cephalexin), a great number of bacteria normally found in the colon are also killed, allowing for the overgrowth of c difficile (resistant to the initial antibiotic used).
Dr. John Leander Po
Dr. John Leander Po
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