6 doctors weighed in:
How’s an aromatase inhibitor used for breast cancer?
6 doctors weighed in

Dr. Sean Canale
Breast Surgery
3 doctors agree
In brief: Hormonal therapy
Aromatase inhibitors are a form of hormonal therapy for post menopausal patients.
They are effective only in er+ cases. They block the conversion of other hormones to estrogen via the enzyme aromatase. In premenopausal patients they actually stimulate the ovaries to increase estrogen production. Hormonal therapy is systemic treatment, reduces local recurrence, and reduces risk of 2nd primaries.

In brief: Hormonal therapy
Aromatase inhibitors are a form of hormonal therapy for post menopausal patients.
They are effective only in er+ cases. They block the conversion of other hormones to estrogen via the enzyme aromatase. In premenopausal patients they actually stimulate the ovaries to increase estrogen production. Hormonal therapy is systemic treatment, reduces local recurrence, and reduces risk of 2nd primaries.
Dr. Sean Canale
Dr. Sean Canale
Thank
Dr. Andrew Turrisi
Radiation Oncology
1 doctor agrees
In brief: It is an anti-
Estrogen used in women after menopause, with tumors that have an estrogen receptor. It is not useful if eh ovaries are generating scads of estrogen.
And tumors without er do not respond to estrogen maneuvers. It also may be useful as a preventive in older women with in situ cancers, but tamoxifen is standard.

In brief: It is an anti-
Estrogen used in women after menopause, with tumors that have an estrogen receptor. It is not useful if eh ovaries are generating scads of estrogen.
And tumors without er do not respond to estrogen maneuvers. It also may be useful as a preventive in older women with in situ cancers, but tamoxifen is standard.
Dr. Andrew Turrisi
Dr. Andrew Turrisi
Thank
Get help from a real doctor now
Dr. Arnon Rubin
Board Certified, Internal Medicine
20 years in practice
162K people helped
Continue
108,000 doctors available
Read more answers from doctors