Extremely rare! High dose steroids 40mg/day or higher, can be associated with steroid psychosis. High doses can agitate and make sleep difficult. Remember the patient have underlying depression, or a serious underlying condition can depress an individual. Yes, it has been reported in pts. On high dose steroids, but rare.
Yes. High-dose Prednisone makes people depressed, and undiagnosed cushing's syndrome, with high steroids made in the body, leads to a disturbing number of suicides. Everyone i've knows who's tried Anabolic steroids for bodybuilding has been sorry; the mood swings are horrible and a person may do something they regret so much they cannot live with themselves.