5 doctors weighed in:

How do bone scan and a pet scan differ?

5 doctors weighed in
Dr. Brian Wosnitzer
Nuclear Medicine
3 doctors agree

In brief: Tracers..

The tracers are different.
Bone scan usually uses TcMDP and PET scan uses F18-FDG (glucose). The bone scan is good for showing osteoblastic bone lesions and shows increased bone activity around a metastasis but not the actual metastasis itself. The PET can show glucose uptake in the actual tumor itself. PET is better for lytic bone lesions. CT part of PET/CT can show lytic and blastic lesions.

In brief: Tracers..

The tracers are different.
Bone scan usually uses TcMDP and PET scan uses F18-FDG (glucose). The bone scan is good for showing osteoblastic bone lesions and shows increased bone activity around a metastasis but not the actual metastasis itself. The PET can show glucose uptake in the actual tumor itself. PET is better for lytic bone lesions. CT part of PET/CT can show lytic and blastic lesions.
Dr. Brian Wosnitzer
Dr. Brian Wosnitzer
Thank
Dr. Gerald Mandell
Nuclear Medicine
1 doctor agrees

In brief: Yes

Bone scan, injection of isotope usually tc99m mdp, detects abnormalities of bone metabolism, infection, fracture, some tumors, highly metabolic bone processes such as pagets disease, bone infarction.
Pet with f18 FDG injection detects changes in glucose metabolism i.e. Tumors and metastases.In general malignant tumors have high glucose metabolism. Fluorine 18 pet scan in some centers for imaging bone.

In brief: Yes

Bone scan, injection of isotope usually tc99m mdp, detects abnormalities of bone metabolism, infection, fracture, some tumors, highly metabolic bone processes such as pagets disease, bone infarction.
Pet with f18 FDG injection detects changes in glucose metabolism i.e. Tumors and metastases.In general malignant tumors have high glucose metabolism. Fluorine 18 pet scan in some centers for imaging bone.
Dr. Gerald Mandell
Dr. Gerald Mandell
Thank
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