How does meningitis affect the endocrine system during and afterwards?

Adrenal collapse. This may occur in Meningococcal sepsis with meningitis (called the waterhouse-friedrickson syndrome), and similar condition may occur with pneumococci in persons with no spleen or with altered antibody production (myeloma, etc.). In any bacterial infection with sepsis there are alterations in glucose metabolism and Insulin and glucogon production, as well as physiological hypoadrenocorticolism.