Focalin (dexmethylphenidate) XR is no longer effective? Any advice?

May need to switch. There are several options available. First option is to switch to a drug of a different class such as adderall. Another option is to get involved in cognitive behavioral therapy specifically designed for add or adhd. Other options are: elavil, norpramin, pamelor, (nortriptyline) tofranil or other tricyclic antidepressants catapres, kapvay, tenex wellbutrin best wishes.