6 doctors weighed in:

Can I have celiac disease even if a skin test showed negative for wheat allergy?

6 doctors weighed in
Dr. Anlin Xu
Internal Medicine - Allergy & Immunology
3 doctors agree

In brief: Definitely

Contrary to common belief, celiac disease is not a "wheat allergy".
It is the body's abnormal immune reaction to gluten, but it is not mediated by the classic antibody that mediates allergic reactions. Skin test to wheat is not the right test for celiac disease. Skin test negative or positive to wheat does not rule out or confirm celiac diz. If u r concerned, ask ur doc for the proper blood test.

In brief: Definitely

Contrary to common belief, celiac disease is not a "wheat allergy".
It is the body's abnormal immune reaction to gluten, but it is not mediated by the classic antibody that mediates allergic reactions. Skin test to wheat is not the right test for celiac disease. Skin test negative or positive to wheat does not rule out or confirm celiac diz. If u r concerned, ask ur doc for the proper blood test.
Dr. Anlin Xu
Dr. Anlin Xu
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Dr. Arthur Heller
Internal Medicine - Gastroenterology
1 doctor agrees

In brief: Get blood test

Skin tests are much better for environmental allergies, e.
g. Pollen, dander, than they are for dietary allergies. Unlikely you have celiac disease if skin tests were negative. However, blood tests, e.g. Deaminated gliadin iga, igg, or transglutaminase iga, with serum IgA level are more accurate screening tests. Genetic testing can help exclude, but not dx; bowel biopsy is needed to confirm dx.

In brief: Get blood test

Skin tests are much better for environmental allergies, e.
g. Pollen, dander, than they are for dietary allergies. Unlikely you have celiac disease if skin tests were negative. However, blood tests, e.g. Deaminated gliadin iga, igg, or transglutaminase iga, with serum IgA level are more accurate screening tests. Genetic testing can help exclude, but not dx; bowel biopsy is needed to confirm dx.
Dr. Arthur Heller
Dr. Arthur Heller
Thank
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