Can a joint stop working if you don't make enough lube?

Joint fluid. Yes. The present of both adequate amount of joint fluid ("lube") and intact joint cartilage are necessary for proper and normal joint motion. I am not aware of any specific medical condition in which the body does not make enough synovial (joint) fluid. The usual problem is that the cartilage gets worn and the joint fluid is not adequate to ensure smooth motion over a very rough joint surface.