Can I take food which contains provitamin-a/ beta-carotene when I am on accutane? Does it cause side effects?

Yes. You don't need to avoid foods containing vitamin a or carotenoids, but you should avoid vitamin a supplements when taking isotretinoin, as any potential toxic effect of vitamin a may be enhanced. This may result in joint and muscle aches, dry skin, abdominal pain, and some effects on the liver.