6 doctors weighed in:

What is (are) the mechanism(s) by which benzodiazepines reduce norepinephrine release?

6 doctors weighed in
Dr. Pamela Pappas
Psychiatry
2 doctors agree

In brief: Benzodiazepines

Benzodiazepines do not directly reduce norepinephrine release, but they do enhance the inhibitory gaba-a receptor function in the brain so that nerve cells downstream will be less active -- including norepinephrine-firing ones.
The end effect is sedation, emotional calming, decreased muscle tone and coordination, decreased memory function, and a host of other changes.

In brief: Benzodiazepines

Benzodiazepines do not directly reduce norepinephrine release, but they do enhance the inhibitory gaba-a receptor function in the brain so that nerve cells downstream will be less active -- including norepinephrine-firing ones.
The end effect is sedation, emotional calming, decreased muscle tone and coordination, decreased memory function, and a host of other changes.
Dr. Pamela Pappas
Dr. Pamela Pappas
Thank
Dr. Donald Jacobson
Psychiatry
2 doctors agree

In brief: Here you go

www.socialanxietysupport.
com/forum/f30/benzodiazepines... Benzodiazepines and their effect on ... By a reduction of norepinephrine activity in a ... Direct impact on Dopamine release. However, the drugs do interact .. It is all much more complicated then we are told in medical school or residency. In fact, it appears that the entire story has not yet been written as far as benzo's are concerned.

In brief: Here you go

www.socialanxietysupport.
com/forum/f30/benzodiazepines... Benzodiazepines and their effect on ... By a reduction of norepinephrine activity in a ... Direct impact on Dopamine release. However, the drugs do interact .. It is all much more complicated then we are told in medical school or residency. In fact, it appears that the entire story has not yet been written as far as benzo's are concerned.
Dr. Donald Jacobson
Dr. Donald Jacobson
Thank
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