Related Questions

If an autoimmune disease is in remission at the time of ANA testing could the test be negative but possibly still have the disease. Eg RA or sle?

Yes. Autoantibody tests can sometimes become negative when the disease is in remission. However, the high likelihood is that the underlying disease is still present. Read more...
Yes. The anti-nuclear antibody (ANA) titer fluctuates over time, and it's also a test fraught with pitfalls within the lab, with results hard to reproduce even from day to day. I'm very glad you asked; this is a thoughtful and important question that touches on how tricky it is to manage these diseases. The key is treat the person, not the lab value. Read more...