Appetite suppressant. Appetite suppressants like fenfluramine, dexfenfluramine, and Diethylpropion increase the risk of pulmonary artery hypertension (pah). Those with pah are more likely to have used appetite suppressants. Cocaine and amphetamines have also been attributed to developing pah.
Anorexic Agents. Dietary suppressants or anorexigens have been linked to an increased risk of developing pulmonary hypertension. The classic agent is Fenfluramine and its derivative, dexfenfluramine. Others include amphetamine derivatives. For additional information and drug names, please refer to dr. Abenhaim's article in the new england journal of medicine august 29, 1996.
A little. Avoiding excessive salt and avoiding or correcting obesity can help but otherwise I'm not aware of any other diet related interventions that are likely to make much difference.
Yes. Pulmonary hypertension can lead to right heart failure. Having a low salt diet and a fluid restriction is very important to avoid heart failure. Having said that, we do not know of any diet that can cure the disease or change its progression.
PH and Diet. A healthy diet is important whether or not you have pulmonary hypertension (ph). Often patients with ph should observe diets low in sodium (salt) and restrictive of high fluid intake. Please discuss your particular dietary needs with your physician.
Possibly. Healthy diet and lifestyle will help, but not likely to cure the disorder. Read: http://www. Nhlbi. Nih. Gov/health/health-topics/topics/pah/livingwith. Html.
Yes. 10-30 % of patients with scleroderma will develop pulmonary hypertension. Regular screening with pulmonary function tests is recommended to monitor for development of pulmonary hypertension. Echo cardiogram of heart is recommended as well as a screening tool.
Yes. Yes it can. In fact patients with the disease should be routinely screened for pulmonary hupertension.
Frequently. Scleroderma can often have pulmonary hypertension (increased pressure in the pulmonary arteries) as a consequence. A common variation of scleroderma called crest syndrome usually includes pulmonary hypertension and it is frequently the most serious part of the disease.
Yes. If pulmonary hypertension occurs, it can severely affect quality of life and may cause premature death. Certain types of scleroderma such as limited cutaneous scleroderma are associated with pulmonary hypertension. Other types such as morphea are not. Screening is essential.
No. Systemic hypertension (blood pressure measured with a cuff on the arm) is not related to pulmonary hypertension (blood pressure estimated/measured with an ultrasound of the heart or right heart catheterization). Having systemic hypertension does not increase the risk for pulmonary hypertension.
Yes. There are many forms of pulmonary hypertension. One of them is called "associated with heart disease". Patients with uncontrolled systemic hypertension are at risk of developing "diastolic dysfunction" and this can then cause pulmonary hypertension.
Yes. Systemic hypertension may lead to a thickened, stiff left ventricle that results in high left heart pressure that is transmitted backwards to the right heart. Such a situation is called pulmonary venous hypertension.
Yes. There are many causes of pulmonary hypertension and one specific cause is from left heart disease. If systemic high blood pressure (hypertension) remains untreated for a long time, it can cause consequences to the left ventricle of the heart and cause problems of relaxation or thickening. This in turn causes high pressure in the left side of the heart and ultimately backup of blood and Pulm Hyptn.
HTN leading to PH. Chronic hypertension can lead to left heart failure (systolic or diastolic) that can lead to pulmonary hypertension (PH) but not normally to pulmonary arterial hypertension (PAH).
Drugs. There are 3 classes of meds currently approved for pulmonary htn. They are endothelin receptor antagonists (tracleer and letairis), pde-4 inhibitors (revatio and adcirca) and prostacyclin analogs (remodulin, flolan, ventavis, (iloprost) and tyvaso). There are other drugs in other classes still under development.
Depends on the cause. There are multiple causes of pulmonary hypertension and based on the cause the treatment should be focused. For group 1 pulmonary hypertension that is caused by idiopathic hypertension (unknown cause) and a positive vasoreactivity test (test to see if the disease responds to the vasodilators) then some vasodilators can be given.
PH Cure. There are 9 available medications for pulmonary arterial hypertension (pah) including phosphodiesterase-5 inhibitors, endothelin receptor blockers and prostaclins. The treatment can be quite effective but does not generally cure pah. Lung transplant can cure the disease but has other significant issues.
Approved by FDA. (VENTAVIS) (ILOPROST Generic Name) is approved by FDA for treatment of Pulmonary Arterial Hypertension (PTH) in World Health Organisation (WHO) Group 1 Patients.
Yes. Adcirca (tadalafil) is a once a day dru called a pde-5 inhibitor. These drugs cause blood vessels to widen, which may result in a decrease in pulmonary hypertension. In original trials with the drug it improved exercise capacity (people can walk further) and decreased the risk for needing lung transplant, hospitalization or other medications.
Yes. Adcirca (tadalafil) is a once a day pde 5 drug similar to viagra and affects the Nitric Oxide pathway for pulm HTN which has deficient Nitric Oxide causing arterial constriction. It may be used alone or with other drugs (eras and prostanoids). The drug is indicated for stage 2/3 pulm htn.
Tadalafil for PH. Fda approved treatments include oral endothelin receptor antagonists (eras), ambrisentan and bosentan; oral phosphodiesterase inhibitors, tadalafil and sildenafil; and prostanoids (iloprost, epoprostenol, and treprostinil). These treatments widen lung blood vessels and ease the symptoms of pulmonary hypertension (ph). Adcirca contains tadalafil.
It depends. It really depends on what is causing the pulmonary hypertension because some advanced cases that is not responding to medication might require a lung or a heart-lung transplant, that doesn't necessarily mean this is the case. I advise you to stay in touch with a cardiologist.
Pulmonary hypertensi. There are a variety of causes for pulmonary hypertension. The treatments for each are not all the same. Even knowing the 'cause' of a case of pulmonary hypertension, the appropriate therapy may not always be effective. Discussing with the treating physician is the best first step. Referral to a Pulmonary hypertension specialty center may be needed.