High am cortisol and hgh. Cortisol am 39.6 with ref range at 4.0 22.0 HGH 11.3with ref range at <8.0 would it explain the inability to lose weight?

Possibly. Were these saliva or blood tests? What are your thyroid tests? It is really difficult to tell without more information. What is your diet and your exercise like? And how long have you been on this diet and exercise regime. How overweight are you and where is the weight distributed? Sorry i can't be of more help now..